Bottles sealed with rubber, for single or multiple doses.

• A. Vials
• B. Ampules
• C. Single-Dose Vials
• D. Multidose Vials

Answer: (A)

Bottles sealed with rubber stoppers are vials. The rubber stopper under a crimp cap allows sterile needles to pierce the seal, letting you withdraw doses multiple times if the vial is designed for multidose use (or just once for a single-dose vial). This packaging is what enables both single-dose and multidose formats.

Ampules, by contrast, are glass containers with a thin neck that’s snapped open to access the contents, and they’re typically used for a single dose. The wording describes vials, not ampules. Single-dose and multidose vials differ mainly in whether multiple entries are intended and sometimes whether a preservative is included to prevent contamination with repeated use.