Effect of medication at the site of administration.

• A. Systemic Effects
• B. Local Action
• C. Global Response
• D. Delayed Effect

Answer: (B)

This item tests whether a drug works at the place it is given rather than traveling through the blood to affect distant tissues. When a medication acts where you apply or administer it, that is local action—the therapeutic effect is confined to the site of administration. If the drug were absorbed and moved through the bloodstream to influence other organs, you’d have systemic effects. Delayed effect refers to timing, not where the action occurs, and a global response isn’t the standard way to describe this concept. So, the effect at the site of administration is best described as local action.